Unrelated to latest chapter, I surprised no one mentioned Butcher as future opponent/antagonist. Because that fucker(s) really hard to pin down. Sure, they don't have anything (canonically) that can damage Joe. But the chaos and destruction they can bring is not to be underestimated. And I don't think Joe currently have anything that can capture them.
Also, there's number of Butchers whose powers canonically unknown (or not specified). So, LordR can give them more or less anything he want (anything that not obvious and flashy, that is, like Thinker powers).
edit: And right after I posted that comment I checked SB and found that Butcher!Taylor fic been updated today.