As far as I'm concerned, the winning move is to spend the Transcendental Boon on b o o k, to spend a Great Deed to open a Branch College with a research focus, and then to spend mundane resources like money and Favor to pay for the Branch College's facilities.
We do not know the estimated cost of College research facilities in mundane resources, but adding a tower to our penthouse costs 100gc base and some combination of additional money (50-100), College Favors (1-5), and Dwarf/Runesmith Favors (1-5), so that maybe gives us an order of magnitude?