I agree with the point about virtue but I grumble about the genre/trope framing of "horror media synopses pitched as interesting experiments", reality doesn't run on genres and sometimes what sounds like a horror media synopsis is a good thing. A real life example went approximately like this:
Around the year 1800, smallpox vaccination had been invented, but electric refrigeration and airplanes were a century away.
How, then, to get the smallpox vaccine to the New World?
We can deliver it as fresh cowpox, thought some clever people.
But cowpox is infectious for less time than it takes a ship to cross the Atlantic.
OK, we'll serially infect people with cowpox on board ship.
But the adults have probably already had it and it's hard to check without spoiling the test subject.
Logic dictates, therefore, we'll have to get young children and serially infect them with fresh cases of cowpox while in transit.
In order to minimize breaking up families and also ensuring the children have the same uninfected status initially, we'll take an entire orphanage population, they would have given each other cowpox at the orphanage if they had it. And their minder, naturally.
But make sure to split up the infected and uninfected ones to ensure transmission proceeds at a controlled pace, so we still have a recent spread of cowpox to the last one by the time we dock.
King Charles of Spain, when he heard this proposal, could have said "Your plan to
infect a chain of orphans to spread a disease to a new continent to fight a worse disease sounds like the start of a horror story and a crime against nature."
But instead he funded the Royal Philanthropic Vaccine Expedition of 1803, possibly influenced by having lost his own daughter to smallpox in 1794, and the first international vaccination campaign took a step towards "
Smallpox was".