Absent Cauldron's meddling, there's no PRT for one thing. There's no Suits, no Red Gauntlet, no Elite Sentai group or whatever I called them, no Elite; all groups that Cauldron set up or supported. Groups are formed but can't sustain themselves past tight Undersider-like groups of 5-10 individuals. Conflicts are more tightly contained and devastating, recovery is slower, and an area that ends up lost or fucked doesn't get the backup needed to revive. Such areas are abandoned or occupied by whatever groups are willing to make do with the aftermath/ongoing occupation by X gang or Y high-level threat.
Non-parahumans in the West end up taking a more aggressive stance against parahumans, as certain voices aren't silenced, and without the Protectorate as an example, things are just more anti-parahuman around the world as a whole. Heroes are fewer and farther between than in conventional Worm - you've got an awful lot of shades of grey and people doing their damndest just to get by. The Chevaliers and Miss Militias of the world are staying right where they are, in small town X or Turkey-occupied Kurdistan, and they're helping their town/country and only their town/country. For the most part, parahumans are taking over where they can take over, and because the population is so hostile, they're forced to be a little ugly or harsh to quell dissent, or they're nice and constantly watching their back/focusing far too much on just keeping things functioning.
Assuming that Cauldron's operatives maybe killed Eden but then just sat on their hands/died, the Endbringers don't exist, the cauldron vials aren't spread out, and there's less of the really powerful parahumans here and there who're capable of acting decisively. Gates to other worlds are left open, feeding into Cote D'Ivorie, spitting out more than a fair share of Case-53 like monsters, only in a very tightly occupied space. If West Africa survives, it's either as a world power or as a mutant-occupied area. If they find Eden's corpse, well, you've got a whole other mess, because they're going to be less careful and organized about it. Assuming they don't accidentally revive Eden, there's going to be a lot of failed doses.
Further, the major threats that Contessa and Number Man deemed too dangerous to leave alone weren't necessarily eliminated (either because Contessa herself didn't pay a visit, or because Cauldron didn't contrive to have said parahuman put down), so there's more Ash Beasts, Blasphemies, Sleepers and the equivalent roaming around.
There's no Parahuman Containment Center, so there's no place to put the really dangerous villains. What do you do with the villains who can't be killed, like Gavel? You maybe try to wrangle some giant-killers like Flechette/Foil, but how many of those guys are there, really?
You're talking about infrastructure, but quite honestly, infrastructure wouldn't survive the 90's. By the mid-2000's, getting food from the agricultural states to the areas with the highest population density (ie. New york) is a struggle, because of bandits, threats, organized crime, disorganized crime and more. Things come to resemble the theoretical Edenverse, but you don't have Eden shoring up the population by putting tinkers and capes capable of reviving areas anywhere particular (you also don't have her sabotaging). Scion ends up playing a pretty big role in keeping society alive, more than before, with keen attention to the biggest threats and only those threats.
By March 2011, half the world is struggling, and the other half is controlled by powerful figures of the Glaistig Uaine class. Richter and his AIs might have a hand in keeping eastern Canada going, but his attention is focused on New York, which is a clusterfuck of the Nth order. A coalition of villains occupy Brockton Bay, including Marquis, the Butcher Queen and the Little Doctor, while outside parties want a piece of that pie. Every second city has a major threat in or near it - not quite on the level of an Echidna or Nilbog, but bad enough that it's hard to put down.
It isn't hopeless, but it's grim. Points of light in a broad swathe of darkness. There is a way out, nobody's actively trying to stop them from finding it, but it's an uphill battle every step of the way.