When they've suddenly lost their powers, are surrounded by hostiles and are stuck in range of the Simurgh, they might as well be as good as dead as far as the rest of the world is concerned. Unless we get the Deus Ex Machina if Scion to combat Simurgh's Diabolos Ex Machina, we can consider this a case of Rocks Fall Everyone Dies. At least you're thorough when you invoke the trope. There's almost no way for us to deal enough damage to the Simurgh to drive her away in time, unless Rust Shooter actually works on her, in which case we're completely fucked as she stops sandbagging. BB gets written off, and anyone leaving gets shot on sight. The Protectorate and the PRT fall apart as Contessa and Number Man try to maintain them in the most "effective" way. It's not like even Cauldron would trust them after such thorough exposure to the Simurgh. One of Contessa's blind spots IS the Endbringers after all. Worldwide Endbringer fight participation drops to an all time low, especially against the Simurgh, now that it's known that she can do this sort of thing. Heck, that last one is likely to happen even if BB doesn't become a quarantine zone. Not many with powers want to experience losing them after all. I wonder what happened to Faultline's crew anyway? When your powers are part of your physical makeup, what happens when you lose them?
Well, we might as well go struggling into the grip of death. We have a miniscule chance of things going well with this option, and even that's only if Simurgh has her precog messed with by the blast, yet it's still better than a 0% chance that other options probably have.
[X] Attack the Simurgh – That staff is the reason this woman is acting like she is. If you can destroy the Simurgh's staff, maybe she'll stop. All it takes is fighting an Endbringer solo.