I'm bored during work so I'm going to build out stuff for Giant Slayer and Epoxy. Wild Speaker just seems like its a potential component in Nepthys, Nox, Chatroom, and Bulwark builds so far rather than a centerpiece, if a potentially good component at that.
Giant Slayer is an 8 potency power that has an innate synergy in Transmutation (in this case changing the size and mass of objects) and Enhanced Strength, so we have 5 points to work with. Most of the 4-5 point options don't seem to have any major synergy powerwise with this barring maybe Epoxy's innate use case of keeping someone stuck in place to be hit power wise. The power that interests me the most when looking at Giant Slayer is Multiplex's, considering the ability to transform themself into an object that does not outweigh your body's mass seems rather interesting when combined with the ability to mess with the size and mass of objects.
Still I think the options here are Multiplex/Sewer Rat/Daggermaw to build out Transformation/Enhanced Strength/Enhanced Senses and some Self Enhancement, or Adamant/Soldier X/Multiplex if trying to build up Autobiokinesis and Enhanced Strength. Maybe Soldier X could fit into the first build over Daggermaw if synergies get discovered, but the second enhanced senses tag and 3rd transformation tag is tempting there.
Its possible that some of the transformation tags might be irrelevant due to being a part of the Transmutation synergy potentially, the bases they're used with are mostly brought brought for their other tags barring Multiplex, which is brought for the powers potentially working together.
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Epoxy is a 5 cost self contained FFM with the power to stick and unstick things together. This is genuinely really powerful since there didn't seem to be any indications that its a melee power only, meaning you can forcibly ground someone to a spot to take whatever you're going for. While FFM is obtainable at 3 cost fairly easily, the baseline power here is what would be wanted if using Epoxy. Where honestly, the bigger issue just seems to be that its a generic piece which can be deployed in most areas?
It'd probably work with long range and flight based options to just have a forcibly stationary target. I could see being mean with like Umibozu/Hydrocity builds by forcibly keeping someone stuck in place as you surround their head in water to take them out of the fight. Maybe use Deadman's magma or Crimson Soprano's flight and energy blasts for some other options?