You'd be amazed at how low my respect for comics understanding of scale goes.
The funny thing is that even at the low end, the scale isn't fit for purpose. Demolishing a large building is largely a question of the placement of your explosives and knocking out load-bearing elements of the structure, not raw energy input. Some well-placed demo-charges can do more damage to a building than a nuclear bomb.
Indeed, notice how large towns that are demolished by earthquakes leave plenty of human survivors. Are we to assume that humans are tougher than towns, because humans can survive earthquakes while towns have more problems with that?
And let's not get started on how inconsistent such feats often are, how characters are frequently concerned about things far below their alleged weight scale, and how high end feats often rely on one off incidents and quotes like "I'M SHOOTING A BEAM THAT COULD DESTROY EVERYTHING THAT IS, WAS, AND WILL BE AT YOU! OH NO YOU BLOCKED IT WOW YOU ARE SO TOUGH".
If you want such a fool's errand, take it to the VS Debates subforum, not here.