No lol. Waste is nasty because of fission products or neutron activation. That's why DU is only a heavy metal toxicity concern. Nasty stuff has short half lives in the decades to centuries range. Long enough it will be a problem for generations, but short enough that it releases lots of energy. Thousands to tens of thousands of stuff is also an issue because it's still highly active and now lasts so long that you can't expect you will be around to keep an eye on it.You think that less fission products is a GOOD thing?
Oh heck no! We want as much of that uranium and plutonium fissioned as we can!
Uranium and especially plutonium are a combination of decently long life, reasonably radioactive and hella toxic chemically. Anything else is an improvement as far as releasing it into the environment.
Like all the scare stories about nuclear waste we've been hearing for all our lives? That's because of the unburned uranium and plutonium in spent nuclear fuel. Which is why recycling nuclear fuel solves so dang many of the problems with nuclear power.
You can carry vastly less propellant if you execute the same missions, but the missions don't change and a Mars mission is really nonviable because of the operational concerns of widely separated launch windows and long travel durations. You need ion engines or exotic nuclear ones to really break open the issue of missions just taking too long. If we are sending people to Mars, we need a faster response than 9 months once a year.Ion engines have limits as to how much thrust you can get out of them. There's also complexity issues with large solar-electric or nuclear-electric ion rockets.
As such, nuclear rockets are very useful in deep space - they are relatively simple, relatively high thrust, and either you can run them on something easily recovered from local resources like water and enjoy ISPs comparable to a hydrolox chemical rocket or you run them on something like hydrogen and enjoy ISPs twice as good, meaning you can get away with carrying VASTLY less propellant.
The tyranny of the rocket equation means that even though solid core nuclear rockets are "only" twice to three times as good ISP-wise as hydrolox, that translates to a much, much, much smaller rocket, meaning you can go to more interesting places and bring more fun tools with you wherever you go, or you can do the same mission as you would with a chemical rocket, but for vastly less cost.
A nuclear rocket basically knocks at least an order of magnitude off of the cost of a Mars mission, for example.
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