In it's severance is despair. In despair lies death.
-This is about Changing.
-It is general, it doesn't care how many it impacts or how important the desire is, only that the desire ends.
-It is a Weapon. It is used to force change upon others, bringing death.
Why does this work?
Life is motion, Want drives motion. Hot moves to Cold, Lightning travels from highest potential to lowest. It doesn't matter what specific attraction is involved here, each individual want that is removed reduces the impetus to motion, and thus moves them towards death.
For an individual, remove the desire to avoid harm, make them forget why they fight, numb their senses to the need to conserve resources for later.
For a group, strike at their commitment, obliterate their agenda so they spiral into blind resource acquisition, or at their greed, so they spend all of themselves.
Example target: Imperial Conservative bloc. Strike at their pride in identity, undermine their xenophobia, and make them feel comfortable such that they don't idealize order and safety. The bloc dissolves...though it doesn't actually do anything about where the components go next, because you don't understand them.