The worst part is they started out with right methods taking volunteers from those who couldn't be saved from conventional methods and trying a risky method to save their lives.Do you mean the part where Cauldron did a lot of good making hard choices, or the part where they gave up on looking for good choices and trying to make things better?
But then once they got entrenched power they did stupid things like nemesis programs and selling to villains who just make things worst