NO. A single sniper bullet is enough. Repeat as needed(factoring threat level and actual necessity). Worst case scenario, drop some JDAMs or use AGTMs.
EDIT:
RE Use of Force and Threat Escalation Levels:
First of all, there is the consideration of who handles the would-be threat actors and their level of danger(obligatory mugger to Yangban). The level of danger ()and it's specific nature determines the magnitude of response ad who handles the response.
Ignoring the obvious day to day threats(which are likely being handled by the local security team), we have the following groups that are likely involved in protecting Taylor:
(List is non-exhaustive)
- NSA- COMINT and SIGINT. Likely will intercept attempts by known and potential threat actors to coordinate attacks/threats. Can be fooled by either not being targeted(Cauldron(needed, else Cauldron would have been picked up on)) and/or very high tier security(difficult, NSA likely backdoored a lot of netcom(eg HTTPS, SSL) standards).
- Secret Service/US Marshall Service-Likely provides for the immediate protection group around Taylor, will get briefed by other authorities involved in the process.
- US Military- Provides additional forces and higher end firepower
- FBI/CIA- Will track down threats(domestic and foreign). Likely cues other on new threats. Also does fieldwork(deterrence and others).
- Various QRF including Hostage rescue- Likely first response to any attack baring the local protection team or Taylor.
Possible Scenarios(Nonexhaustive list):
- Local threat actor: Ranges from a random parahuman to Coil Dealt with at lowest level possible by local authorities(with an eye to following up on PRT response as needed). Escalate as needed
- State Level: Anything like the Fallen(endbringer worshippers) Dealt with by a small operation if caught early(eg when said actors are planning an attack). Else there is the likely deployment of QRF groups that have been prepositioned.
- Global/Highest level: Yangban to Cauldron Likely dealt with by the higher end forces(FBI/CIA/NSA/US military). At the minimum, the threat that they pose will be suppressed by these forces' efforts.
At no level should nukes be used unless explicitly necessary. Also, the groups assigned to Taylor's protection are not likely to act unless they have to. They want to keep Taylor secret as much as possible.
Removing riff-raff and secretly threatening local threats?
Doable and already done.
Immediately killing all of the high end villains like Lung and Hookwolf?
No. Doing so would create a dangerous power vacuum (making it hard to detect threats) and let loose more information about what is happening to BB.