I think now is a good time to remember that, in-universe, it's only been less than a full year since we arrived in Earth-Bet, and in that intervening time, we've given it a real kick up the pants in becoming less of a hellhole.
Now, as for other thoughts...
Just spitballing here, but if we could swing it, if he was amenable/amiable enough, and if we wouldn't mind owing Israel a pretty big favor in the process, would it be possible to negotiate a deal with En Kamoni to get him to go after Kamikoe?
He has experience in taking out Master-led cults, he himself is immune to Master effects, and it would be a good idea to talk the strongest cape in a region onto our side.
Or an alternate solution, would Ninja Roja be amenable for a semi-long-term infiltration op if we quietly locate and subdue Kamikoe and get her to replace her? The thing about cults is that if everyone is so slavish to the dear leader, if they were quietly replaced with a lookalike and started acting a bit differently, would the members start to suspect the dear leader, or just change their beliefs/actions to match because they've been doing so for years, power or no power? If this works, we might be able to keep the Kamikoe situation contained/controlled enough for the JSDF to handle it themselves or until we take care of one more operation (then again, despite her name, I doubt Ninja Roja knows Japanese or has a way of getting the knowledge fast enough).
I think the issue right now is that it seems like unless we/the Guild take an active look into situations and actively decide to help them along, things just don't take steps in good directions by anyone other than us taking initiative, even now that we've given them the opportunity to do so with a global surge of optimism; they either remain stagnant or backslide.
I mean, the ceasefire between Black Sun and Phosphor was good, but it backslid until we poked our head in. Bastion both survived the Leviathan attack and managed to wipe away his scandal with the victory, but he went right back to shooting his mouth off later and we had to bail him out. The Nigeria/Kenya situation is on a delicate balance of favor/repayment and might topple if we take our eyes off of it, even though we advocated for the release of democratic activists to help stabilize the situation. Liberating Brazil and handling Gesellschaft are ongoing missions that will actively lose progress and support if we don't handle them.
Now that we've given everyone a boost, are they reciprocating in kind and matching our efforts? Were there any JSDF heroes that would've been able to do something against Kamikoe, but weren't because they were tied up in keeping an eye on Skylance or Fuji-Sama? Are there folks who have been railing against Gesellschaft for years who have now gotten more support now that the Avatar is kicking them in the side? Are there officials in the Nigerian and Kenyan governments who are actively normalizing relations between them that don't need us wiping their noses?
Has there been anyone from anywhere in the world who's had the Avatar help them, resolve their situation, then say, "You've given us a real chance. Don't worry, we'll take it from here."? The only place that we seem to have 90+% completion and is in a relatively stable state is Brockton Bay itself.
But maybe I'm over-complaining. This was always going to be a dynamic quest, and creating plans to resolve as many problems as possible was always the main draw. Though maybe we were hoping that some problems would be resolved by now and we wouldn't have to keep going back to them...
Which is why Sun's Discount Light-Slash-League Of Supervillains is the quest's proper BBEG: We have no idea they exist, they can build up at their leisure, and can make a global counteroffensive. The S9 were a sideshow. GS is a third-stringer. Even that shit idea called the Chinese Union-Imperial isn't that much of an issue. We're basically fighting a dozen brushfire wars with an on-the-fly organizational buildup until The Evil Avengers decide to introduce themselves.
Don't forget the incoming three Endbringer pileup.
Maybe we'll get lucky and one of the Endbringers will pop up under one of the Lords' home cities and take them off the board via collateral damage. \doubt