To be fair, she right.
Anyway, back to Arcane.
We can all figure that Vi will be uterly devestated to learn that Vander has become a menacing murderbeast now called Warwick.
But what about the other Zaunites that knew the ol "Hound of the Underground?"
Jinx, Ekko, Sevika, Babette (the prostitute yordle) knew the guy. Now he's back, bigger and furrier and more ferocious then ever and with the wicked claws to boot.
If anything........out of currently known characters I think the major bosses for the season will be Singed, Warwick and Ambessa, and in the end Vi, Jinx, and Ekko break away to follow their new lives for a bittersweet ending.