A quest where, after the Paradox ending of Inevitable Excess dlc for Pathfinder: Wrath of the Righteous, the Knight Commander awakens in the Mindflayer ship next to the Dark Urge with strange case of amnesia, the voices of her companions in her head, and mythic powers seemingly reset to zero and made even more malleable than ever. Decide if, in this new world, you will reach out to Angels or Demons, or perhaps if you turn into a terrifying chimera of mythic aspects, you already shouldn't exist anyway so why not continue breaking everything?
Spoilers for WotR, obviously. Starts at the very beginning of BG3 so no spoilers for that yet but in future it could change. Knowledge of BG3 is not necessary, Knight Commander knows even less of the setting than you do. Knowledge of WotR... Probably a good idea or you won't know what's the deal with any of the WotR companions, but probably not necessary either? And absolutely no need for knowledge about mechanics of either DnD5E or either edition of PF.
Spoilers for WotR, obviously. Starts at the very beginning of BG3 so no spoilers for that yet but in future it could change. Knowledge of BG3 is not necessary, Knight Commander knows even less of the setting than you do. Knowledge of WotR... Probably a good idea or you won't know what's the deal with any of the WotR companions, but probably not necessary either? And absolutely no need for knowledge about mechanics of either DnD5E or either edition of PF.