Our missiles probably outrange it's ion cannons, so... Though the Tiamat does have good acceleration profiles from what we know, so it is anyone's guess as to how the upcoming fight might go.I think the useful questions for this approach are: Do we have a range advantage on Ninhursag? Can we actually hurt it from that range? Is it faster than us to chase us down if we try this?
If our missiles connect I don't see how they wouldn't do damage, smashing capitals was what they were designed for.