No living human does, sure, but we don't even know if living humans have souls, at this point. In reality they're unmeasurable speculation at best, so far.
In a setting where a soul is an actual thing with identifiable effects, the story obviously becomes wildly different, heh. If you're dealing with a setting that's supposed to be non-magical or whatev', soul stuff is going to be a silly thing to include. If you're not dealing with that (and boy howdy is The Gamer setting in particular not dealing with that, though whether it's the power of souls or the power of magic genetics wasn't something that had been made clear up to the point I last caught up with it, heh), well... you're not dealing with that. Soul stuff may become a point of note.
... totes agree soul mate/bond stuff specifically tends to be a major negative, though. I can't recall ever encountering something that wasn't substantially worsened by its inclusion in the story, heh, for a whole pile of different reasons. Better just to leave that out.