I will start with predictions.
The obvious place to begin is the pair of Kraken and Coil. They are thematically opposite: he views himself as a superhero and she sees herself as a classy villain. They have a personal reason for a clash: he is a good friend and an ex of detective Patch, while she wants to get rid of her. He wants for his siblings to reunite and return to the time when they were heroes; she wants to use her new siblings to do the dirty work for her, get her haul and return to being a solo thief. I can see them facing off against each other with the help of one other sibling, and the heroes to get their heads out of their asses and work together to win while villains will fight each other as much as heroes.
I can see Automaton becoming part of the Seventh's plotline. She wants to be a part of her family, but the circumstances (the lack of power) and their unwillingness to include her drive her off. He doesn't want any part of it, but the circumstances (his daughter's illness) and his new "family" forces him into this conflict. She will always be the seventh and he will always be the fifth, one of but not, the last and the least.
Both Seance and Blackout don't want to have their power and use outside means (drugs and rugs) to block and hide it. Additionally, Seance cannot get rid of Horror haunting him, while Blackout has to stick with her "family" to get help. I can see them being Kraken and Coil's sidekicks.
Rumour's usage of her powers led to her losing her family. Now she voluntarily chooses not to use them. Wretch's powers wouldn't let her to live her life as she wants. Now she let it go and voluntarily uses them. Spaceboy was loyal and dutiful to his father till latter's death, and now is unmoored. Wretch was alone for her whole life, but now she has a brother and she will not let him go. I can see Rumour's power suppressing Ilya and not working on the animalistic mind of a Wretch, who is additionally strong enough to fight Spaceboy to a standstill.
The fight of the Boy and Undying all but guaranteed. The question is what each of them are willing to sacrifice and use in order to win.
In the past, your characters were like a single character, but with different life experiences, if it makes sense? They each had their motivations and goals, but in the core they were a same person. Now they are more distinct and fleshed out beyond their backstories. I can believe that each of them have their own favourite song and they don't match.
I liked Ilya and Wretch a fair bit. But I was under impression that to use the power she has to become more Wretch than Ilya, while she later in the story uses her animalistic powers while remaining sentient.
Unsurprisingly, I liked Alfredo the most of the bunch. He was made to be sympathetic. I find Coil to be a little too childish for a woman in her thirties. Elanor was good, but a little unrelatable at the moment due to her circumstances. I will have to relate to her through her interactions with other characters in the future. Same problem with Ulysses, he has a fair share of character traits (driven, obsessive, vengeful, persuasive, etc) but none of them is particularly relatable. He either needs to become pure evil (and for that he needs to be more fun) or develop some relatable traits (fall in love with someone, or protect someone, or even like dogs).
Keep up good work, you are doing great!