The day after the Eighteenth Amendment (Prohibition) is ratified. New drugs start appearing in every drugstore in the world. The ingredients of these drugs are rare, but present on Earth. These drugs give mammals amazing abilities, but they generally come at a major cost. These drugs are taken in pill form with each tablet containing 50 milligrams of the substance. The drugs fully activate 30 minutes after ingestion. The user gains the power for 12 hours. Afterwards, there is a tapering off period of 30 minutes where the power slowly disappears. Then there is a 6 hour "hangover" period where the user suffers a migraine and an additional negative side effect (varies based on the pill).
If a user takes more than 150 mg of superpills within a 30 day period, they will likely become addicted. The consequences of addiction are cravings, insomnia, anxiety, and irritability. If an addict doesn't take at least 25 mg of their superpill every 72 hours, they will die a slow and painful death. Taking 100 milligrams or two pills within a short time frame increases the potency (generally by 25%) and duration of the power (generally by 50%), but it also increases the hangover period as well (generally by 50%) and virtually guarantees addiction. Taking more than 200 milligrams of a superpill within 24 hours will almost certainly lead to the death of the user and potentially others near the user.
Superpills also provide the required secondary superpowers to use the abilities properly. Here are the superpills:
Drug_Name
Ability
High-dosage effects
Specific Drawback
Stronex
Super Strength (2000 kg)
Average man can now lift 2,500 kg
Diarrhea
Velocira
Super Speed (500 kph)
Average man can now run 625 kph.
Vertigo
Invulnex
Super Durability (any attack less than or equal to a pistol-caliber round in kinetic energy is resisted. You are also immune to pain).
You are invulnerable to any attack weaker than a small (5.56x45mm) rifle-caliber round.
Your body becomes hypersensitive and you lose all pain resistance.
Aquabliss
Waterbreathing
You can also survive the water pressure of the deep ocean.
You suffer from Altitude Sickness
Aerion
Flight (200 kph)
User can fly at 250 kph
You feel and become very heavy
Pyroflux
Fire Breath (The user breathes out hot fire with the intensity and range of a M1 flamethrower).
The range and intensity is upgraded to a M2 flamethrower.
You suffer from hypothermia
Neurolink
Motor-Skill Manipulation (You can override the motor functions of up to one person you can see).
You can override two people at once.
You have a grand Mal seizure.
Spectrafade
Invisibility (from visible light)
Your clothes are also invisible
Your skin turns a bright purple.
Omnisight
EM Spectrum Vision
You can see living auras.
You become blind.
Melange
Agelessness
You age backwards.
You randomly lose memories.
Mentaview
Telepathy (range of 50 meters)
Telepathy (150 meters)
Your thoughts are projected to nearby people
Prophesia
Prescience (1 day)
Prescience (1 week)
You become unlucky
So how would the world change if pills that could do these were around in the early 1900s? Would prohibition on these drugs last indefinitely? Would cartels and mobs make a killing on the black market? Will these super drugs be used in warfare? Will animals be given these pills? Feel free to come up with more superpills as well.