Who would Guilliman pick if he had the choice; cloned fem!Konrad, or cloned fem!Angron.
Choice between the two brothers he liked the least and found genuinely insane (though he also had troubles "understanding" their respective issues)?
Both committed atrocities on Ultramar, but Konrad was more personal about it.
Still, Guilliman desperately yearned for a brother to share the burdens he had to take up. His inner monologs and interactions with Mortarion and Magnus made it clear that he regretted how things went down.
Overall? We don't really have a chance with anyone inside the Imperium except for Guilliman and he wouldn't care as much about the Xeno thing. Holding such a force together will be much more difficult. Being a Primarch will get the humans and Astrates to follow us, but for how long? Being a Konrad Clone will impact their perception, as will taking Xenos along.
As for the aliens? The Eldar will want to return to their own kind and the rest is likely in conflict with humanity, or at least humanity is in conflict with them by default. So taking the Xenos means our force cohesion, which is already going to be shaky by being of Traitor Blood, will potentially further plummet.
On the other hand this is an opportunity to do something Konrad never did or had to do: be inspiring and rallying people to him (her now I suppose) through charisma and personality. We will likely involve some fear to deal with the more stupid ones (that's the easy part), but we should definitely take a note from Machiavelli and add some reasons for people to follow her out of respect/love as well.
Edit: I'm pretty sure Trazyn's planet is in the Eastern Fringe of the galaxy, which means we are likely in what is, or is going to be, Imperium Nihilus. If we do want to go Renegade, there's no better place than that.