Hmmm...
That could impact our choice-making in regards to where we settle in Eriador. If women are expecting half-orc children, and do not want to terminate the pregnancies, we could decide to settle closer to lands where that'd be less of a problem... I imagine whatever Angmarim hillsmen remain in Aughaire would be less averse to that happenstance than the Gondorians, and they could use Numenorean craftsmen and fresh blood.
Or maybe... Can we choose to settle under Saruman's rule(he should already have Isengard's keys by the time of the desertion of Ithilien)? That would be pretty interesting.